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Heart disease gene found

Genetic variations may explain why some are more at risk of heart disease

Variations in a gene that acts as master switch for other genes may affect how likely a person is to develop heart disease, according to new US research.

The discovery, by a team at Duke University Medical Center, could soon lead to a genetic test to predict an individual's risk.

Those found to be at high risk will then be able to modify their behaviour and take steps to reduce their chances of becoming ill.

According to the National Heart Forum, Coronary heart disease (CHD) is the leading single cause of death in the UK and it will claim the lives of one in four men and one in six women. In addition, it can cause years of disability and ill health.

However, mortality rates from CHD have been falling in the UK since the late 1970s. In 1983 coronary heart disease was responsible for 150,000 deaths in the UK annually, but by 2003 this number had decreased to 120,000.

Here are some ways that you can reduce your risk of developing CHD:

Reduce your saturated fat intake

Eating a lot of foods that are high in saturated fats - mostly from animal rather than vegetable - sources can raise the level of 'bad' LDL cholesterol in your blood, so try to avoid or cut down on fatty food such as red meat, butter, whole milk, cheese, cakes and chips.

Eat a healthy diet

Oily fish such as herring, kippers, mackerel, pilchards, salmon, sardines and trout contain oils that can lessen the risk of blood clots.

Many vegetables, fruit and cereals contain anti-oxidant vitamins (beta-carotene and vitamins C and E), which prevent saturated fats from being changed into cholesterol in your body.

You should try and take 30 minutes' brisk exercise five times a week. Walking is an excellent way to stay fit. Buy a pedometer and try and do 10,000 steps each day.

Stop smoking

Smoking is a major risk factor of coronary heart disease because it hardens the arteries, causing them to narrow (arteriosclerosis). Smoking causes the majority of cases of coronary thrombosis in people under 50.

Limit your alcohol intake

Try to stick to your recommended daily allowance (three to four units a day for men and two to three units a day for women) and avoid binge drinking.

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Information on this site is for interest only and is not a substitute for professional medical advice. You should consult your own doctor about any specific health concerns.

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